Mr.Santhosh Kumar N

Mr.Santhosh Kumar N

Research Scholar
Area: Bioinformatics
Email ID: santhoshkumar.nv@ktr.srmuniv.ac.in

Affiliation: Department of Genetic Engineering, Kattankulathur Campus, SRM Institute of Science and Technology (formerly known as SRM University)

Education

Other Details:

Research Interests:

• Molecular modelling and Computer Aided drug designing
• Protein and lipid membrane dynamics
• 3D QSAR and Density Functional Theory

Selected Publications:

• Santhosh Kumar N, Sathya B, and Thirumurthy M. (2017). Theoretical analysis of somatostatin receptor 5 with antagonists and agonists for the treatment of neuroendocrine tumors. Molecular Diversity, 21(2), pp.367-384.
• Santhosh Kumar N, Sathya B, Sohn H, Panneer D, and Thirumurthy M, (2017). 3D-QSAR studies on indole and 7-azoindole derivatives as ROCK-2 inhibitors: An integrative computational approach. Computational Biology and Chemistry, 71, pp.104-116.
• Sathya B, Santhosh Kumar N, Hang Lee S, and Thirumurthy M, (2016). Structural characterization of human CRTh2: a combined homology modeling, molecular docking and 3D-QSAR-based in silico approach. Medicinal Chemistry Research, 25(4), pp.653-671.
• Abinaya B, Manish B, Meenakumari S, Thirumavalavan M, Thirumurthy M, Santhosh Kumar N, Velusamy P and Pachaiappan R (2018). Isolation, purification and characterization of proteinaceous fungal α-amylase inhibitor from rhizome of Cheilocostus speciosus (J.Koenig) C.D.Specht. International Journal of Biological Macromolecules, 111, pp.39-51.
• Sathya B, Rupa M, Santhosh Kumar N, Sohn H, and Thirumurthy M, (2016). Molecular Modeling Study on Diazine Indole Acetic Acid Derivatives for CRTH2 Inhibitory Activity. Combinatorial Chemistry & High Throughput Screening, 19(6), pp.444-460.

Work in Progress:

• Structural characterization of Somatostatin receptors using apo and complex structures in a solvated lipid bilayer microenvironment
• Performing 3D QSAR, DFT calculations to check for modifications in ligand conformation for better activity.

Achievements and Awards:

• Qualified GATE 2011 and 2012
• Qualified CSIR-NET 2015