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Toxicology Testing

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SRM Central Animal House facility offers the following Standard Toxicology studies also to fulfill academic and regulatory requirements.

A.  Short Term Studies

1. Acute Oral Toxicity in Rat & Mice
2. Acute Toxicity Studies by IV - Rat & Mice
3. Acute Toxicity Studies by SC - Rat & Mice
4. Acute oral toxicity MTD/LD50 in Rat & Mice
5. Acute toxicity MTD/LD50 by IP in Mice
6. Primary skin Irritation - Rabbit
7. Acute Eye Irritation - Rabbit
8. Acute Dermal Toxicity
9. Cytotoxicity

B.   Repeated Dose Studies

1. Oral, Dermal, IV, SC, IP in Mice and Rats
2. Skin Sensitization - direct application in Guinea pigs
3. Reproductive Toxicology
C.   Biocompatibility Studies for Medical Devices
1. Implantation in Rat- 1 week
2. Implantation in Rat- 2 weeks
3. Implantation in Rat- 4 weeks
4. Implantation Rabbit - 1 week
5. Implantation Rabbit - 2 weeks
6. Implantation Rabbit - 4 weeks
7. Implantation Rabbit - 12 weeks


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